Ontology highlight
ABSTRACT:
SUBMITTER: Tara Charlie Marcink
PROVIDER: EMPIAR-10476 | biostudies-other |
REPOSITORIES: biostudies-other
Marcink Tara C TC Wang Tong T des Georges Amedee A Porotto Matteo M Moscona Anne A
PLoS pathogens 20200921 9
Infection by human parainfluenza viruses (HPIVs) causes widespread lower respiratory diseases, including croup, bronchiolitis, and pneumonia, and there are no vaccines or effective treatments for these viruses. HPIV3 is a member of the Respirovirus species of the Paramyxoviridae family. These viruses are pleomorphic, enveloped viruses with genomes composed of single-stranded negative-sense RNA. During viral entry, the first step of infection, the viral fusion complex, comprised of the receptor-b ...[more]