Ontology highlight
ABSTRACT:
SUBMITTER: Fukagawa Tatsuo
PROVIDER: EMPIAR-10565 | biostudies-other |
REPOSITORIES: biostudies-other
Ariyoshi Mariko M Makino Fumiaki F Watanabe Reito R Nakagawa Reiko R Kato Takayuki T Namba Keiichi K Arimura Yasuhiro Y Fujita Risa R Kurumizaka Hitoshi H Okumura Ei-Ichi EI Hara Masatoshi M Fukagawa Tatsuo T
The EMBO journal 20210119 5
The CENP-A nucleosome is a key structure for kinetochore assembly. Once the CENP-A nucleosome is established in the centromere, additional proteins recognize the CENP-A nucleosome to form a kinetochore. CENP-C and CENP-N are CENP-A binding proteins. We previously demonstrated that vertebrate CENP-C binding to the CENP-A nucleosome is regulated by CDK1-mediated CENP-C phosphorylation. However, it is still unknown how the phosphorylation of CENP-C regulates its binding to CENP-A. It is also not co ...[more]