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Atomic resolution structure of apoferritin from Titan Mono/BCorr microscope


ABSTRACT:

SUBMITTER: Holger Stark 

PROVIDER: EMPIAR-10591 | biostudies-other |

REPOSITORIES: biostudies-other

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Publications

Atomic-resolution protein structure determination by cryo-EM.

Yip Ka Man KM   Fischer Niels N   Paknia Elham E   Chari Ashwin A   Stark Holger H  

Nature 20201021 7832


Single-particle electron cryo-microscopy (cryo-EM) is a powerful method for solving the three-dimensional structures of biological macromolecules. The technological development of transmission electron microscopes, detectors and automated procedures in combination with user-friendly image processing software and ever-increasing computational power have made cryo-EM a successful and expanding technology over the past decade<sup>1</sup>. At resolutions better than 4 Å, atomic model building starts  ...[more]

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