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Tilt-series taken from SARS-CoV-2 infected Vero cells.


ABSTRACT:

SUBMITTER: Luiza Montenegro Mendonca 

PROVIDER: EMPIAR-10753 | biostudies-other |

REPOSITORIES: biostudies-other

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Since the outbreak of the SARS-CoV-2 pandemic, there have been intense structural studies on purified viral components and inactivated viruses. However, structural and ultrastructural evidence on how the SARS-CoV-2 infection progresses in the native cellular context is scarce, and there is a lack of comprehensive knowledge on the SARS-CoV-2 replicative cycle. To correlate cytopathic events induced by SARS-CoV-2 with virus replication processes in frozen-hydrated cells, we established a unique mu  ...[more]

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