Cryo-electron tomograms of RPE1 cells with comprehensive annotation of actin filaments and microtubules
Ontology highlight
ABSTRACT:
SUBMITTER: Julia Mahamid
PROVIDER: EMPIAR-10989 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Stress fibres are embedded in a contractile cortical network.
Vignaud Timothée T Copos Calina C Leterrier Christophe C Toro-Nahuelpan Mauricio M Tseng Qingzong Q Mahamid Julia J Blanchoin Laurent L Mogilner Alex A Théry Manuel M Kurzawa Laetitia L
Nature materials 20201019 3
Contractile actomyosin networks are responsible for the production of intracellular forces. There is increasing evidence that bundles of actin filaments form interconnected and interconvertible structures with the rest of the network. In this study, we explored the mechanical impact of these interconnections on the production and distribution of traction forces throughout the cell. By using a combination of hydrogel micropatterning, traction force microscopy and laser photoablation, we measured ...[more]
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