Dataset Information
Single-particle reconstruction of Tick-borne encephalitis virus (Preparation 1)
Ontology highlight
ABSTRACT:
SUBMITTER: Sarah Jane Butcher
PROVIDER: EMPIAR-11032 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Molecular Organisation of Tick-Borne Encephalitis Virus.
Viruses 20220411 4
Tick-borne encephalitis virus (TBEV) is a pathogenic, enveloped, positive-stranded RNA virus in the family <i>Flaviviridae</i>. Structural studies of flavivirus virions have primarily focused on mosquito-borne species, with only one cryo-electron microscopy (cryo-EM) structure of a tick-borne species published. Here, we present a 3.3 Å cryo-EM structure of the TBEV virion of the Kuutsalo-14 isolate, confirming the overall organisation of the virus. We observe conformational switching of the peri ...[more]
