Ontology highlight
ABSTRACT:
SUBMITTER: Simon James White
PROVIDER: EMPIAR-11201 | biostudies-other |
REPOSITORIES: biostudies-other
Structure (London, England : 1993) 20230116 3
Many double-stranded DNA viruses, including tailed bacteriophages (phages) and herpesviruses, use the HK97-fold in their major capsid protein to make the capsomers of the icosahedral viral capsid. After the genome packaging at near-crystalline densities, the capsid is subjected to a major expansion and stabilization step that allows it to withstand environmental stresses and internal high pressure. Several different mechanisms for stabilizing the capsid have been structurally characterized, but ...[more]