Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling - dataset2
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ABSTRACT:
SUBMITTER: Hauke S. Hillen
PROVIDER: EMPIAR-11317 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Cryo-EM for Structure Determination of Mitochondrial Ribosome Samples.
Methods in molecular biology (Clifton, N.J.) 20230101
Single-particle cryoelectron microscopy (cryo-EM) allows structure determination of large macromolecular complexes from conformationally and compositionally heterogeneous mixtures of particles. This technique has been used to reveal the architecture of the mitochondrial ribosome and to visualize transient states that occur during the translation cycle or during mitoribosome biogenesis. Here, we outline an exemplary workflow for the analysis of single-particle cryo-EM data of human mitoribosome s ...[more]
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