Purified tails from bacteriophage T5 after interaction with E. coli receptor FhuA inserted into nanodiscs - dataset 2
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ABSTRACT:
SUBMITTER: Romain Linares
PROVIDER: EMPIAR-11327 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Structural basis of bacteriophage T5 infection trigger and <i>E. coli</i> cell wall perforation.
Linares Romain R Arnaud Charles-Adrien CA Effantin Grégory G Darnault Claudine C Epalle Nathan Hugo NH Boeri Erba Elisabetta E Schoehn Guy G Breyton Cécile C
Science advances 20230324 12
Most bacteriophages present a tail allowing host recognition, cell wall perforation, and viral DNA channeling from the capsid to the infected bacterium cytoplasm. The majority of tailed phages bear a long flexible tail (<i>Siphoviridae</i>) at the tip of which receptor binding proteins (RBPs) specifically interact with their host, triggering infection. In siphophage T5, the unique RBP is located at the extremity of a central fiber. We present the structures of T5 tail tip, determined by cryo-ele ...[more]
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