Cryo electron tomography of whole mitochondria and released crista membranes isolated from Caenorhabditis elegans
Ontology highlight
ABSTRACT:
SUBMITTER: Vicki Gold
PROVIDER: EMPIAR-11542 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
The consequence of ATP synthase dimer angle on mitochondrial morphology studied by cryo-electron tomography.
Buzzard Emma E McLaren Mathew M Bragoszewski Piotr P Brancaccio Andrea A Ford Holly H Daum Bertram B Kuwabara Patricia P Collinson Ian I Gold Vicki V
The Biochemical journal 20240102
Mitochondrial ATP synthases form rows of dimers, which induce membrane curvature to give cristae their characteristic lamellar or tubular morphology. The angle formed between the central stalks of ATP synthase dimers varies between species. Using cryo-electron tomography and sub-tomogram averaging, we determined the structure of the ATP synthase dimer from the nematode worm C. elegans and show that the dimer angle differs from previously determined structures. The consequences of this species-sp ...[more]
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