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3D reconstructions of parasite development and the intracellular niche of the microsporidian pathogen E. intestinalis


ABSTRACT:

SUBMITTER: Gira Bhabha 

PROVIDER: EMPIAR-11683 | biostudies-other |

REPOSITORIES: biostudies-other

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3D reconstructions of parasite development and the intracellular niche of the microsporidian pathogen <i>E. intestinalis</i>.

Antao Noelle V NV   Lam Cherry C   Davydov Ari A   Riggi Margot M   Sall Joseph J   Petzold Christopher C   Liang Feng-Xia FX   Iwasa Janet J   Ekiert Damian C DC   Bhabha Gira G  

bioRxiv : the preprint server for biology 20230702


Microsporidia are an early-diverging group of fungal pathogens that infect a wide range of hosts. Several microsporidian species infect humans, and infections can lead to fatal disease in immunocompromised individuals. As obligate intracellular parasites with highly reduced genomes, microsporidia are dependent on metabolites from their hosts for successful replication and development. Our knowledge of how microsporidian parasites develop inside the host remains rudimentary, and our understanding  ...[more]

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