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Training Set for CryoVesNet - Cryo-electron tomograms of rat synaptosomes and synaptic vesicle segmentation


ABSTRACT:

SUBMITTER: Amin Khosrozadeh 

PROVIDER: EMPIAR-12195 | biostudies-other |

REPOSITORIES: biostudies-other

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Publications

CryoVesNet: A dedicated framework for synaptic vesicle segmentation in cryo-electron tomograms.

Khosrozadeh Amin A   Seeger Raphaela R   Witz Guillaume G   Radecke Julika J   Sørensen Jakob B JB   Zuber Benoît B  

The Journal of cell biology 20241024 1


Cryo-electron tomography (cryo-ET) has the potential to reveal cell structure down to atomic resolution. Nevertheless, cellular cryo-ET data is highly complex, requiring image segmentation for visualization and quantification of subcellular structures. Due to noise and anisotropic resolution in cryo-ET data, automatic segmentation based on classical computer vision approaches usually does not perform satisfactorily. Communication between neurons relies on neurotransmitter-filled synaptic vesicle  ...[more]

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