Project description:In this article, we employ simple descriptive methods in order to explore the peculiar behavior of the symbols in the Voynich Manuscript. Such an analysis reveals a group of symbols which are further analyzed for the possibility of being compounds (or ligatures), using a specifically developed method. The results suggest the possibility that the alphabet of the manuscript is a lot smaller, and steganographic type of encoding is proposed to explain the newly revealed properties.
Project description:Computational pipelines have become a crucial part of modern drug discovery campaigns. Setting up and maintaining such pipelines, however, can be challenging and time-consuming-especially for novice scientists in this domain. TeachOpenCADD is a platform that aims to teach domain-specific skills and to provide pipeline templates as starting points for research projects. We offer Python-based solutions for common tasks in cheminformatics and structural bioinformatics in the form of Jupyter notebooks, based on open source resources only. Including the 12 newly released additions, TeachOpenCADD now contains 22 notebooks that cover both theoretical background as well as hands-on programming. To promote reproducible and reusable research, we apply software best practices to our notebooks such as testing with automated continuous integration and adhering to the idiomatic Python style. The new TeachOpenCADD website is available at https://projects.volkamerlab.org/teachopencadd and all code is deposited on GitHub.
Project description:Lamb waves and meteotsunamis generated by the Tonga volcanic eruption in 2022 were observed worldwide. Here, we show a distinct spectral peak at approximately 3.6 millihertz in the air and seafloor pressures of those waves. The peak in the air pressure represents resonant coupling between Lamb and thermospheric gravity waves. To reproduce the observed spectral structure up to 4 millihertz, an upward-moving pressure source with a duration of 1500 seconds should be placed at altitudes of 58 to 70 kilometers, which are slightly higher than the overshooting plume top of 50 to 57 kilometers. The high-frequency meteotsunamis forced by the coupled wave are further amplified by near resonance with the tsunami mode upon their passage through the deep Japan Trench. From the spectral structure of broadband Lamb waves including the 3.6-millihertz peak, we suggest that the pressure sources for generating the Pacific-scale air-sea disturbances are in the mesosphere.