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Figure 7. Long-lasting antitumor T-cell memory induced by a single Lenti-HPV-07 vaccination

ABSTRACT: Lenti-HPV-treated and cured mice which have been re-challenged with TC-1 cells (n = 5/group), received at day 286 post tumor engraftment an i.v. injection of an adjuvant-free mixture of E7HPV16:ETTDPDRAHYNIVTF and E7HPV16:PDRAHYNIVTFCCKC peptides (25 µg of each/mouse). Naïve control mice received the same i.v. treatment. At 48h post injection, splenocytes were stimulated in vitro with homologous or negative control peptides during 6h prior to IFN-g ICS and surface labeling.

ORGANISM(S): Mus musculus (mouse)

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PROVIDER: S-BSST1108 | biostudies-other |

REPOSITORIES: biostudies-other

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