Unknown

Dataset Information

0

Transcription profiling by array of A549 lung carcinoma cells expressing the transcription factor Nkx2-1

ABSTRACT: A transcription factor Nkx2-1 (also known as TTF-1) regulates the expression of different sets of genes. Gene expression analysis was performed using mRNAs from Nkx2-1-induced A549 cells compared to that from the control A549 cells. We used microarrays to detail the global program of gene expression controlled by Nkx2-1 and identified distinct classes of up-regulated and down-regulated genes. mRNAs were isolated from control and Nkx2-1-induced A549 cells and hybridized on Affymetrix microarrays. We sought to identify genes influenced by Nkx2-1.

ORGANISM(S): Homo sapiens

SUBMITTER: Maeda Yutaka 

PROVIDER: S-ECPF-GEOD-40584 | biostudies-other |

REPOSITORIES: biostudies-other

Json Xml

Similar Datasets

Unknown Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells.
| S-EPMC5451263 | biostudies-literature
Transcriptomics Analysis of Nkx2-1-regulated gene expression in A549 lung carcinoma cells
2012-09-05 | E-GEOD-40584 | biostudies-arrayexpress
Transcriptomics Analysis of Nkx2-1-regulated gene expression in A549 lung carcinoma cells
2012-09-05 | GSE40584 | GEO
Unknown [Screening metastasis-associated genes from anoikis resistant A549 lung cancer cells by human genome array].
| S-EPMC6000681 | biostudies-literature
Unknown Gene expression profiling of cancer stem cell in human lung adenocarcinoma A549 cells.
| S-EPMC2234429 | biostudies-literature
Unknown The Roles and Regulatory Mechanisms of Tight Junction Protein Cingulin and Transcription Factor Forkhead Box Protein O1 in Human Lung Adenocarcinoma A549 Cells and Normal Lung Epithelial Cells.
| S-EPMC10855320 | biostudies-literature
Unknown Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo.
| S-EPMC8096971 | biostudies-literature
Unknown Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer.
| S-EPMC10147615 | biostudies-literature
Unknown Non-thermal plasma treatment altered gene expression profiling in non-small-cell lung cancer A549 cells.
| S-EPMC4483225 | biostudies-literature
Unknown Human Blood Extracellular Vesicles Activate Transcription of NF-kB-Dependent Genes in A549 Lung Adenocarcinoma Cells.
| S-EPMC9777395 | biostudies-literature