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Transcription profiling of human lung cancer cell lines


ABSTRACT: Anticancer drug clustering in lung cancer based on gene expression profiles. We performed gene expression analysis in lung cancer cell lines. (used: Affymetrix GeneChip Human Genome U133 Array Set HG-U133A). We also examines the sensitivity of these cell lines to commonly used anti-cancer agents (docetaxel, paclitaxel, gemcitabine, vinorelbine, 5-FU, SN38, cisplatin, and carboplatin) via MTT assay. We related the cytoxic activity of each of these agents to corresponding expression pattern in each of the cell lines using modified NCI program. Experiment Overall Design: gene expression analysis in lung cancer cell lines

ORGANISM(S): Homo sapiens

SUBMITTER: Gemma Akihiko 

PROVIDER: S-ECPF-GEOD-4127 | biostudies-other |

REPOSITORIES: biostudies-other

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