Unknown

Dataset Information

0

Identify the cancer stem cells expression characteristics in ovarian and breast cancer

ABSTRACT: The identification and characterization of subpopulations of cancer stem cells (CSCs) provide new understandings and possible therapeutic implications in cancer biology. We found the ovarian cancer sphere cells possessed CSCs properties maintained self renewal, drug resistance, and tumorigenesis. Using high-throughput microarray system, we identified common GO terms and pathway signatures significantly enriched in ovarian and breast cancer stem cells. Ovarian and breast cancer cells were cultured in sphere formation conditions, and total RNA from those spheres and conresponding adhered cell was hybridized on Affymetrix microarrays.

ORGANISM(S): Homo sapiens

SUBMITTER: wang haiwei 

PROVIDER: S-ECPF-GEOD-43657 | biostudies-other |

REPOSITORIES: biostudies-other

Json Xml

Similar Datasets

Transcriptomics Identify the cancer stem cells expression characteristics in ovarian and breast cancer
2013-11-25 | E-GEOD-43657 | biostudies-arrayexpress
Unknown Breast cancers, mammary stem cells, and cancer stem cells, characteristics, and hypotheses.
| S-EPMC7586061 | biostudies-literature
Unknown Molecular characteristics of cancer stem-like cells derived from human breast cancer cells.
| S-EPMC3600631 | biostudies-literature
Unknown Characteristics of CD133-Sustained Chemoresistant Cancer Stem-Like Cells in Human Ovarian Carcinoma.
| S-EPMC7554888 | biostudies-literature
Unknown A Novel ALDH1A1 Inhibitor Targets Cells with Stem Cell Characteristics in Ovarian Cancer.
| S-EPMC6521036 | biostudies-literature
Unknown Connexin46 Expression Enhances Cancer Stem Cell and Epithelial-to-Mesenchymal Transition Characteristics of Human Breast Cancer MCF-7 Cells.
| S-EPMC8624448 | biostudies-literature
Unknown FOXP1 functions as an oncogene in promoting cancer stem cell-like characteristics in ovarian cancer cells.
| S-EPMC4823123 | biostudies-literature
Unknown Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics
| S-ECPF-GEOD-24460 | biostudies-other
Unknown Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells.
| S-EPMC3164893 | biostudies-literature
Unknown The side population of ovarian cancer cells defines a heterogeneous compartment exhibiting stem cell characteristics.
| S-EPMC4196181 | biostudies-other