Human breast cancer SKBr-3 cells: trastuzumab-resistant vs. parental
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ABSTRACT: Human breast cancer SKBr-3 cells selected with trastuzumab for 6 month compared with parental SKBr-3 cells; Goal was to screen for microRNAs involved in development of trastuzumab resistance. Human breast cancer SKBr-3 cells were continuously cultured in the presence of 5µg/ml trastuzumab for 6 months, and the resulting alive cells were regarded as trastuzumab-resistant. Total RNAs were prepared from these cells and cells cultured in parallel in control media, and were subjected to hybridization on the miRCURY LNA Array (Exiqon, version 11.0).
ORGANISM(S): Homo sapiens
SUBMITTER: Jia Lin-Tao
PROVIDER: S-ECPF-GEOD-47011 | biostudies-other |
REPOSITORIES: biostudies-other
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