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Next Generation Sequencing of MCF-7 and MDA-MB-435 cells


ABSTRACT: Human breast cancer cells MDA-MB-435 had higher metastatic potential and other aggressive characteristics than MCF-7 cells. Next-generation RNA sequencing (RNA-Seq) was used to clear this concern through comparison the transcriptomic expression profiles of these two cells. Total RNA were extracted from MCF-7 and MDA-MB-435S cells, and the polyA+ mRNA was sequenced using Illumina Genome Analyzer IIx. The reads were mapped to RefSeq RNA reference sequences.

ORGANISM(S): Homo sapiens

SUBMITTER: Wang Cuihua 

PROVIDER: S-ECPF-GEOD-54122 | biostudies-other |

REPOSITORIES: biostudies-other