Combination of epigenetic, differentiation and DNA damaging agents induce tumor cell death and stem cell depletion in breast cancer

ABSTRACT: Gene expression profiles were performed on MDA-MB-231 TNBC cell line treated with entinostast, all-trans retinoic acid (ATRA), and doxorubicin as single, double, and triple combinations using Illumina. Treatment signatures were made from each drug treatment and integrated to find a comprehensive view of changes associated with the epigenetic, differentiation and chemotherapy combination

ORGANISM(S): Homo sapiens

SUBMITTER: Sukumar Saraswati 

PROVIDER: S-ECPF-GEOD-63351 | biostudies-other |

REPOSITORIES: biostudies-other