Transcription profiling by array of NCI-H460 cells grown as spheres or in adherent conditions
Ontology highlight
ABSTRACT: In this study, we provide evidence that spheroids cells isolated from established human NSCLC cell lines are highly enriched in NSCLC-TICs that aberrant Akt-IL6-Stat3 signalling axis is necessary for self-renewal of lung TICs in vitro and for tumor formation in vivo.
ORGANISM(S): Homo sapiens
SUBMITTER: Viglietto Giuseppe
PROVIDER: S-ECPF-MTAB-1699 | biostudies-other |
REPOSITORIES: biostudies-other
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