Ontology highlight
ABSTRACT:
SUBMITTER: Wu CL
PROVIDER: S-EPMC1051506 | biostudies-other | 1998 Dec
REPOSITORIES: biostudies-other
Journal of medical genetics 19981201 12
Patients who present with unilateral vestibular schwannomas either at a young age or with additional features of type 2 neurofibromatosis (NF2) are at risk of developing bilateral disease and transmitting a risk of neurogenic tumours to their offspring. We have identified 15 patients from a series of 537 with unilateral vestibular schwannomas who also had one or more of the following: other tumours (10/15), features of NF2 (3/15), or a family history of neurogenic tumours (5/15). No germline NF2 ...[more]