Ontology highlight
ABSTRACT:
SUBMITTER: Sutherland BW
PROVIDER: S-EPMC1084121 | biostudies-other | 2001 Nov
REPOSITORIES: biostudies-other
EMBO reports 20011017 11
Previously characterized Ras subfamily proteins have been found to be predominantly associated with the plasma membrane where they function in signal transduction pathways to convey extracellular signals to intracellular targets. Here, we provide evidence that the Dictyostelium Ras subfamily protein RasB has a novel subcellular localization and function. The protein is predominantly localized in the nucleus during most of the cell cycle. Furthermore, during mitosis and cytokinesis RasB assumes a ...[more]