Unknown

Dataset Information

0

Formation in vitro of the 3,4,6-trihydroxyphenylalanine quinone cofactor.


ABSTRACT: An Escherichia coli K-12 2-phenylethylamine oxidase gene with a mutated leader sequence region produced a largely inactive form of the enzyme in the cytoplasm. This form of the enzyme was activated 30-50-fold on incubation at 30 degrees C in the absence of any added cofactors. After activation the enzyme contained a quinone which was not detected in the non-activated form. This is the first report of the formation in vitro of any quinoenzyme cofactor.

SUBMITTER: Hanlon SP 

PROVIDER: S-EPMC1136567 | biostudies-other | 1995 Mar

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC7736144 | biostudies-literature
| S-EPMC4818003 | biostudies-literature
| S-EPMC1147747 | biostudies-other
| S-EPMC3021175 | biostudies-literature
| S-EPMC7193901 | biostudies-literature
| S-EPMC3334298 | biostudies-literature
| S-EPMC7442744 | biostudies-literature
| S-EPMC1147602 | biostudies-other
| S-EPMC7245091 | biostudies-literature
| S-EPMC4443348 | biostudies-literature