Reconstituted collagen fibrils. Fibrillar and molecular stability of the collagen upon maturation in vitro.

ABSTRACT: During the maturation in vitro of reconstituted collagen fibrils prepared from rat skin, the mechanical and thermal stability of collagen increased and the pepsin-solubility decreased. At the same time a larger fraction of the pepsin-soluble collagen attained a lower molecular thermal stability that resulted in a biphasic thermal transition of the soluble collagen. Type-I collagen, with a similar biphasic thermal transition, was isolated from acid-insoluble rat skin collagen.

SUBMITTER: Danielsen CC 

PROVIDER: S-EPMC1144228 | biostudies-other | 1984 Sep

REPOSITORIES: biostudies-other