Unknown

Dataset Information

0

Isolation of a novel cell-attachment and spreading-promoting protein from human serum.


ABSTRACT: A protein with potent cell-attachment and spreading-promoting activity was isolated from fibronectin-free human serum. The purification steps included affinity chromatography on heparin-agarose and preparative isoelectric focusing. The purified protein was homogeneous as judged from dodecyl sulphate/polyacrylamide-gel electrophoresis. It had an isoelectric point of 5.0 and an Mr of 52 000. The protein promoted the spreading of Chinese-hamster ovary cells to plastic in a manner similar to that observed with fibronectin.

SUBMITTER: Vuento M 

PROVIDER: S-EPMC1144861 | biostudies-other | 1985 Apr

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC8427643 | biostudies-literature
| S-EPMC6165858 | biostudies-literature
| S-EPMC1161360 | biostudies-other
| S-EPMC8428749 | biostudies-literature
| S-EPMC3180258 | biostudies-literature
| S-EPMC3744483 | biostudies-literature
| S-EPMC4540119 | biostudies-literature
| S-EPMC3146398 | biostudies-literature
| S-EPMC1635363 | biostudies-literature
| S-EPMC130365 | biostudies-literature