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Progress-curve analysis in enzyme kinetics. Numerical solution of integrated rate equations.


ABSTRACT: Progress curves of enzyme-catalysed reactions are described by equations of a type that precludes direct calculation of the extent of reaction at any time. Previously, such equations have been solved by the Newton-Raphson method, but this procedure may fail when based upon the usual formulae. An alternative formulation is proposed that is both quicker and more robust.

SUBMITTER: Duggleby RG 

PROVIDER: S-EPMC1146728 | biostudies-other | 1986 Apr

REPOSITORIES: biostudies-other