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The exponential model for a regulatory enzyme. An interpretation of the linear free-energy relationship.


ABSTRACT: A physical mechanism is suggested to explain the linear free-energy relationship employed in the exponential model for a regulatory enzyme [Ainsworth (1977) J. Theor. Biol. 68, 391-413]. The interpretation depends on the assumption that the structure of the enzyme changes in proportion to its saturation by substrate but at a rate that is low compared with the rates of the association-dissociation reactions of the enzyme-substrate system.

SUBMITTER: Ainsworth S 

PROVIDER: S-EPMC1147491 | biostudies-other | 1986 Dec

REPOSITORIES: biostudies-other

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