Graphical and statistical analysis of hyperbolic tight-binding inhibition.
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ABSTRACT: Equations are described for the analysis of enzyme-catalysed reactions in the presence of hyperbolic tight-binding inhibitors using both graphical and non-linear-regression methods. The general character of the equations allows the interpretation of several other kinetic mechanisms. As an example, the tight-binding hyperbolic non-competitive inhibition of human leucocyte elastase by a polysulphated glycosaminoglycan is analysed.
SUBMITTER: Baici A
PROVIDER: S-EPMC1148066 | biostudies-other | 1987 Jun
REPOSITORIES: biostudies-other
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