Liver microsomal membrane fluidity and lipid characteristics in vitamin A-deficient rats.

ABSTRACT: Rat liver microsomes (microsomal fraction) were isolated from vitamin A-deficient and -sufficient rats and analysed for membrane lipid characteristics. Membrane fluidity was found to be significantly decreased in microsomes from the vitamin A-deficient rats, but not in liposomes prepared from lipid extracts. Microsomes from vitamin A-deficient animals showed a significant decrease in C18:2, omega 6 and an increase in C22:5, omega 6 fatty acids.

SUBMITTER: Hamm MW 

PROVIDER: S-EPMC1148216 | biostudies-other | 1987 Aug

REPOSITORIES: biostudies-other