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Histamine H2 receptors on foetal-bovine articular chondrocytes.


ABSTRACT: The dose-response curve of histamine-induced cyclic AMP elevation in monolayer cultures of primary foetal-bovine articular chondrocytes was displaced to the right by cimetidine. In addition, H2 but not H1 antagonists prevented the histamine-induced cyclic AMP elevation, suggesting histamine activates chondrocyte adenylate cyclase through an H2 receptor.

SUBMITTER: Taylor DJ 

PROVIDER: S-EPMC1152075 | biostudies-other | 1983 May

REPOSITORIES: biostudies-other

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