UDP-glucuronyltransferase activity exhibits two developmental groups in liver from foetal rhesus monkeys.

ABSTRACT: UDP-glucuronyltransferase was assayed in liver from adult rhesus monkeys and foetuses during late gestation. Activities toward 2-aminophenol, 5-hydroxytryptamine, 1-naphthol and 4-nitrophenol in the foetal liver ranged from 46 to 114% of adult values, whereas activities toward bilirubin, oestradiol and testosterone were less than 5% of adult values. This suggests that in primates UDP-glucuronyltransferase develops differentially in two clusters analogous to that in the rat.

SUBMITTER: Leakey JE 

PROVIDER: S-EPMC1152346 | biostudies-other | 1983 Sep

REPOSITORIES: biostudies-other