Unknown

Dataset Information

0

The effect of starvation and refeeding on lipogenic enzymes in mammary glands and livers of lactating rats.


ABSTRACT: Lactating rats were starved for 48 h and refed a high-carbohydrate diet for a further 48 h. Starvation stops milk secretion, which resumes shortly after refeeding. Three lipogenic enzymes, fatty acid synthase, glucose 6-phosphate dehydrogenase (EC 1.1.1.49) and 'malic' enzyme (EC 1.1.1.40) all decrease in the mammary gland during starvation and are restored to the pre-starvation levels 48 h after refeeding. The same enzymes in liver also decrease during starvation, but increase to values significantly higher than those for the normal fed rats after refeeding the high-carbohydrate diet. For the fatty acid synthase these values were four times the pre-starvation values. Serum insulin and prolactin concentrations also increased upon refeeding the high-carbohydrate diet.

SUBMITTER: Grigor MR 

PROVIDER: S-EPMC1152534 | biostudies-other | 1983 Nov

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC1152022 | biostudies-other
| S-EPMC1185961 | biostudies-other
| S-EPMC1152510 | biostudies-other
| S-EPMC4600687 | biostudies-literature
| S-EPMC1163225 | biostudies-other
| S-EPMC1154010 | biostudies-other
| S-EPMC3551688 | biostudies-literature
| S-EPMC1185410 | biostudies-other
| S-EPMC3806118 | biostudies-literature
| S-EPMC1186521 | biostudies-other