Unknown

Dataset Information

0

Regulation of lipogenesis in vivo by glucose availability and insulin secretion in maternal and foetal tissues during late gestation in the rat. Effect of glucose intubation, streptozotocin-induced diabetes and starvation.


ABSTRACT: Administration of an oral load of glucose did not change the rate of lipogenesis in maternal liver during late gestation. However, streptozotocin-induced diabetes or starvation decreased maternal liver lipogenesis at 20-22 days of gestation. Glucose intubation, on the other hand, increased foetal lipogenesis at 21-22 days. In addition, maternal starvation decreased foetal lipogenesis and plasma insulin concentration. However, chronic hyperglycaemia induced by streptozotocin administration to the mother did not change foetal liver lipogenesis.

SUBMITTER: Lorenzo M 

PROVIDER: S-EPMC1152564 | biostudies-other | 1983 Dec

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC1163268 | biostudies-other
| S-EPMC1158432 | biostudies-other
| S-EPMC3561147 | biostudies-literature
| S-EPMC4121661 | biostudies-literature
| S-EPMC4807697 | biostudies-literature
| S-EPMC3926113 | biostudies-literature
| S-EPMC3416710 | biostudies-literature
| S-EPMC1147250 | biostudies-other
| S-EPMC3851480 | biostudies-literature
| S-EPMC2739698 | biostudies-literature