The reaction of glutathione with the eye-lens protein gamma-crystallin.
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ABSTRACT: Lens cells contain high concentrations of thiol-rich proteins, gamma-crystallins and reduced glutathione. Solutions of bovine gamma-crystallin react avidly with either reduced or oxidized glutathione to form protein-glutathione mixed disulphides. A method of purification of a gamma-II crystallin-glutathione adduct containing two mixed disulphide groups is described.
SUBMITTER: Slingsby C
PROVIDER: S-EPMC1152597 | biostudies-other | 1985 Aug
REPOSITORIES: biostudies-other
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