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Effects of the cyanine dye 3,3'-dipropylthiocarbocyanine on mitochondrial energy conservation.


ABSTRACT: Mitochondrial respiration and oxidative phosphorylation were inhibited by the membrane potential probe 3,3'-dipropylthiocarbocyanine [diS-C3-(5)]. Evidence is presented that suggests that the dye acts as both an inhibitor of electron transport and an uncoupler of oxidative phosphorylation.

SUBMITTER: Howard PH 

PROVIDER: S-EPMC1161108 | biostudies-other | 1979 Jun

REPOSITORIES: biostudies-other

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