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Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals.


ABSTRACT: Iron--EDTA was shown to catalyse OH. production from H2O2 and ascorbate by a mechanism largely independent of superoxide. When ascorbate and superoxide were both present, the ascorbate mechanism was more important than superoxide as a source of OH., and would appear to be more significantly biologically.

SUBMITTER: Winterbourn CC 

PROVIDER: S-EPMC1161347 | biostudies-other | 1979 Aug

REPOSITORIES: biostudies-other

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