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Regulation of tyrosine aminotransferase in foetal rat liver.

ABSTRACT: A specific tyrosine aminotransferase, separate from the aspartate aminotransferases, is present in low concentration in foetal rat liver at the 21st day of gestation. Intraperitoneal injections of tyrosine methyl ester into the foetuses in utero increase the activity 2-fold, whereas glucose injections decrease it. Tyrosine, dexamethasone and dibutyryl cyclic AMP induce the enzyme activity in organ culture to the same extent as in adult rat liver in vivo.

SUBMITTER: Andersson SM

PROVIDER: S-EPMC1161615 | biostudies-other | 1980 Feb

REPOSITORIES: biostudies-other

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Factors affecting the premature induction of tyrosine aminotransferase in foetal rat liver.

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