Unknown

Dataset Information

0

Sheep gastric mucins as a source of blood-group-I and -i antigens.


ABSTRACT: Gastric-mucosal glycoproteins of sheep have been shown to express the blood-group-I and -i antigens. The highest blood-group-I activities were found in glycoproteins lacking in blood-group-A and -H activities. In antigenically very active glycoprotein preparations, approx. 25% of the macromolecules expressed various blood-group-I and -i antigens, and these could be enriched by affinity chromatography with an anti-(blood group I) immunoadsorbent column. Additional blood-group-I and -i activities could be revealed by one cycle of Smith degradation of blood-group-A-active sheep gastric glycoproteins. Thus sheep gastric mucins are an abundant source of oligosaccharides with blood-group-I- and -i-active sequences.

SUBMITTER: Wood E 

PROVIDER: S-EPMC1162455 | biostudies-other | 1980 Jun

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC5902424 | biostudies-literature
| S-EPMC6158591 | biostudies-literature
| S-EPMC5625272 | biostudies-literature
| S-EPMC4338890 | biostudies-literature
| S-EPMC3784667 | biostudies-literature
| S-EPMC9382375 | biostudies-literature
| S-EPMC3555502 | biostudies-literature
| S-EPMC6656718 | biostudies-literature
| S-EPMC3149758 | biostudies-literature
| S-EPMC8315233 | biostudies-literature