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Tricarboxylic acid cycle flux and enzyme activities in the isolated working rat heart.


ABSTRACT: Flux through the tricarboxylic acid cycle was calculated from oxygen consumption in hearts perfused near the physiological work load. Activities of citrate synthase, 2-oxoglutarate dehydrogenase and succinate dehydrogenase were measured in the same hearts. Only the activities of 2-oxoglutarate dehydrogenase correlated with calculated fluxes through the cycle.

SUBMITTER: Cooney GJ 

PROVIDER: S-EPMC1163594 | biostudies-other | 1981 Dec

REPOSITORIES: biostudies-other

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