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Alternative products in the reaction of 2-nitro-5-thiocyanatobenzoic acid with thiol groups.


ABSTRACT: 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives. Evidence was obtained for formation of both the S-cyano derivative and the mixed disulphide derivative. Formation of the S-cyano derivative can be promoted by addition of excess of CN-to the reaction mixture.

SUBMITTER: Price NC 

PROVIDER: S-EPMC1164054 | biostudies-other | 1976 Oct

REPOSITORIES: biostudies-other

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