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The synthesis of hyaluronic acid by sheep and rabbit articular cartilage in vitro.

ABSTRACT: Standard methods of glycosaminoglycan separation were used to confirm the presence of hyaluronic acid in sheep and rabbit articular cartilage. During incubation of carilage in vitro in the presence of [1-14 C]acetate, cartilage cells synthesize this macromolecule and, under the conditions used, it appears to have a shorter turnover time than chondroitin suplhate in the same tissue. The possible functions of hyaluronic acid in cartilage are discussed.

SUBMITTER: Gillard GC 

PROVIDER: S-EPMC1165209 | biostudies-other | 1975 Feb

REPOSITORIES: biostudies-other

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