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Effect of allylisopropylacetamide on Nuclear Ribonucleic Acid synthesis in rat liver.


ABSTRACT: The porphyrogenic drug allylisopropylacetamide, a potent inducer of delta-aminolaevulinate synthetase, specifically increases nucleoplasmic RNA synthesis in rat liver. The drug-mediated increase in nucleoplasmic RNA synthesis is blocked by cycloheximide and haemin, which also inhibit the enzyme induction.

SUBMITTER: Sardana MK 

PROVIDER: S-EPMC1165390 | biostudies-other | 1975 Apr

REPOSITORIES: biostudies-other

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