Preferential inhibition by poly(adenylic acid) of minus-strand synthesis by bacteriophage Qbeta ribonucleic acid replicase.
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ABSTRACT: Among the homopolymers examined, poly(A) was found to inhibit preferentially the synthesis of the minus strand by bacteriophage Qbeta RNA replicase in the presence of host factor. A specific interaction of poly(A) with the host factor is suggested to be a principal cause for the observed preferential inhibition by poly(A) of the host-factor-requiring Qbeta RNA replicase reaction.
SUBMITTER: Kondo M
PROVIDER: S-EPMC1172856 | biostudies-other | 1976 May
REPOSITORIES: biostudies-other
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