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Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human.

ABSTRACT: We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three species (M. mulatta, M. fascicularis, and M. nemestrina) were sampled, resulting in the generation of 48,642 sequence reads. These data represent an initial sampling of the putative rhesus orthologs for 6,216 human genes. Mean nucleotide diversity within M. mulatta and sequence divergence among M. fascicularis, M. nemestrina, and M. mulatta are also reported.

SUBMITTER: Magness CL

PROVIDER: S-EPMC1175991 | biostudies-other | 2005

REPOSITORIES: biostudies-other

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Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human.

Magness Charles L CL Fellin P Campion PC Thomas Matthew J MJ Korth Marcus J MJ Agy Michael B MB Proll Sean C SC Fitzgibbon Matthew M Scherer Christina A CA Miner Douglas G DG Katze Michael G MG Iadonato Shawn P SP

Genome biology 20050630 7

We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three species (M. mulatta, M. fascicularis, and M. nemestrina) were sampled, resulting in the generation of 48,642 sequence reads. These data represent an initial sampling of the putative rhesus orthologs for 6,216 human genes. Mean nucleotide diversity within M. mulatta and sequence divergence among M. fascicularis, M. nemestrina, and M. mulatta are ...[more]

PMID: 15998449

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