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Proteinase inhibitors of bovine nasal cartilage.

ABSTRACT: Extracts from bovine nasal cartilage with 1 M-guanidinium chloride were fractionated by ultrafiltration. Gel chromatography of the low-molecular-weight material resolved three distinct fractions with inhibitory activity against (a) collagenases (22000 mol.wt.), (b) thiol proteinases cathepsin B and papain (13000 mol.wt.), and (c) trypsin and other serine proteinases (7000 mol.wt.).

SUBMITTER: Roughley PJ

PROVIDER: S-EPMC1183848 | biostudies-other | 1978 Mar

REPOSITORIES: biostudies-other

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