6 beta-Bromopenicillanic acid inactivates beta-lactamase I.
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ABSTRACT: The inactivation of beta-lactamase I by preparations of 6alpha-bromopenicillanic acid showed unexpected kinetic features that indicated that the active species was the 6beta-epimer. Samples containing 6beta-bromopenicillanic acid have been synthesized and shown to inactivate the enzyme in a rapid stoicheiometric reaction.
SUBMITTER: Knott-Hunziker V
PROVIDER: S-EPMC1186377 | biostudies-other | 1979 Jan
REPOSITORIES: biostudies-other
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