Ontology highlight
ABSTRACT:
SUBMITTER: Salz HK
PROVIDER: S-EPMC1205864 | biostudies-other | 1994 Mar
REPOSITORIES: biostudies-other
Salz H K HK Flickinger T W TW Mittendorf E E Pellicena-Palle A A Petschek J P JP Albrecht E B EB
Genetics 19940301 3
This study describes the identification, function and molecular characterization of deadhead, a Drosophila thioredoxin homolog. Although in vitro studies have shown that thioredoxin can post-translationally regulate the activity of many different proteins, we find that this homolog is not essential for viability. The phenotypic analysis of two different mutations which eliminate function suggests that dhd is essential for female meiosis. The majority of eggs laid by females homozygous for null m ...[more]