Overproduction of three genes leads to camphor resistance and chromosome condensation in Escherichia coli.
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ABSTRACT:
SUBMITTER: Hu KH
PROVIDER: S-EPMC1207417 | biostudies-other | 1996 Aug
REPOSITORIES: biostudies-other
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Overproduction of three genes leads to camphor resistance and chromosome condensation in Escherichia coli.
Hu K H KH Liu E E Dean K K Gingras M M DeGraff W W Trun N J NJ
Genetics 19960801 4
We isolated and characterized three genes, crcA, cspE and crcB, which when present in high copy confer camphor resistance on a cell and suppress mutations in the chromosomal partition gene mukB. Both phenotypes require the same genes. Unlike chromosomal camphor resistant mutants, high copy number crcA, cspE and crcB do not result in an increase in the ploidy of the cells. The cspE gene has been previously identified as a cold shock-like protein with homologues in all organisms tested. We also de ...[more]
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