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Phosphatidylserine-mediated adhesion of T-cells to endothelial cells.


ABSTRACT: Phosphatidylserine was exposed on the surface of human umbilical endothelial cells (ECV304) a few minutes after adding thrombin in vitro, as monitored by prothrombinase assays with and without annexin V. Jurkat T cells adhered to the thrombin-treated cells. The adhesion was inhibited by annexin V, indicating that it was mediated by exposed phosphatidylserine on the endothelial cells.

SUBMITTER: Qu J 

PROVIDER: S-EPMC1217493 | biostudies-other | 1996 Jul

REPOSITORIES: biostudies-other

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